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N-[(9H-氟-9-甲氧基)羰基]-L-戊基-N-[4-(羟甲基)苯基]-L-丙氨酰胺

Fmoc-Val-ala-PAB

CAS: 1394238-91-5

Molecular Formula: C30H33N3O5

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N-[(9H-氟-9-甲氧基)羰基]-L-戊基-N-[4-(羟甲基)苯基]-L-丙氨酰胺 - Names and Identifiers

Name Fmoc-Val-ala-PAB
Synonyms CS-2746
Fmoc-Val-ala-PAB
Fmoc-Val-Ala-PAB-OH
1-Butanesulfonicacid,6-hydroxy-
Fmoc-Val-Ala-PAB-OH, 9-fluorenylmethyloxycarbonyl-valyl-alanyl-4-aminobenzylalcohol
L-Alaninamide, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-valyl-N-[4-(hydroxymethyl)phenyl]-
(9H-Fluoren-9-yl)methyl ((S)-1-(((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxopropan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate
CAS 1394238-91-5

N-[(9H-氟-9-甲氧基)羰基]-L-戊基-N-[4-(羟甲基)苯基]-L-丙氨酰胺 - Physico-chemical Properties

Molecular FormulaC30H33N3O5
Molar Mass515.6
Melting Point218 °C(dec.)
Solubility DMSO: 10 mM( < 1 mg/ml refers to the product slightly soluble or insoluble)
Storage Condition-20℃
UseFmoc-Val-Ala-PAB-OH is a degradable (cleavable) ADC linker that can be used to synthesize antibody-coupled drugs (ADC).
TargetADCs Linker
In vitro study ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
In vivo studyThe ADC is composed of an antibody, and the ADC cytotoxin is bound to the antibody via the ADC linker.

N-[(9H-氟-9-甲氧基)羰基]-L-戊基-N-[4-(羟甲基)苯基]-L-丙氨酰胺 - Preparation solution concentration reference

 1mg5mg10mg
1 mM1.939 ml9.697 ml19.395 ml
5 mM0.388 ml1.939 ml3.879 ml
10 mM0.194 ml0.97 ml1.939 ml
5 mM0.039 ml0.194 ml0.388 ml
Last Update:2024-01-02 23:10:35

N-[(9H-氟-9-甲氧基)羰基]-L-戊基-N-[4-(羟甲基)苯基]-L-丙氨酰胺 - Introduction

Fmoc-Val-ala-PAB is an organic compound with the chemical formula C12H15N3O2. The following is a description of the nature, use, preparation and safety information of the Fmoc-Val-ala-PAB:

Nature:
-Appearance: Fmoc-Val-ala-PAB in the form of a white or white-like solid.
-Solubility: It is soluble in some organic solvents, such as methanol, dimethyl sulfoxide and dichloromethane.

Use:
- Fmoc-Val-ala-PAB is widely used in the pharmaceutical field of drug research and development.
-It has anti-inflammatory and anti-tumor activities, and is used to develop new drug treatment options.

Preparation Method:
-The preparation of this compound is more complex and usually requires an organic synthetic chemist to synthesize it.
-The preparation process may use a variety of synthetic routes, such as reaction, structural modification and purification.

Safety Information:
-The safe use and handling of Fmoc-Val-ala-PAB must follow chemical safety practices.
-This compound may be toxic to humans, so proper safety measures such as gloves, glasses and protective clothing should be taken when handling.
-Before use, you should understand the toxicity data and safe handling methods of the compound, and ensure that it is operated in a suitable laboratory environment.
- Fmoc-Val-ala-PAB also need to be stored in a cool, dry, well-ventilated place, and away from fire and flammable substances.
Last Update:2024-04-09 20:49:11
N-[(9H-氟-9-甲氧基)羰基]-L-戊基-N-[4-(羟甲基)苯基]-L-丙氨酰胺
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MedChemExpress (MCE)
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Product Name: Fmoc-Val-Ala-PAB-OH Visit Supplier Webpage Request for quotation
CAS: 1394238-91-5
Tel: 609-228-6898
Email: sales@medchemexpress.com
     tech@medchemexpress.com
Mobile: 609-228-6898
SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: Fmoc-Val-Ala-PAB-OH Visit Supplier Webpage Request for quotation
CAS: 1394238-91-5
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
Wechat: 18621343501
WhatsApp: +86-18621343501
Shanghai Macklin Biochemical Co., Ltd
Spot supply
Product Name: Fmoc-Val-Ala-PAB-OH Visit Supplier Webpage Request for quotation
CAS: 1394238-91-5
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
Shanghai Yuanye Bio-Technology Co., Ltd.
Product Name: Fmoc-Val-ala-PAB Visit Supplier Webpage Request for quotation
CAS: 1394238-91-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
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